Innovative Bioreactor
Solutions for Efficient
Data Integration

Handy. Smart. Flexible.

Our bench-top modular bioreactor is ideal for daily work and offers unparalleled high quality. It enables data-driven decision-making, sets new standards in control and automation, prioritizes user-centric safety, and features an ergonomic design.

Ideal for a wide variety of applications, from
fermentation to cell culture. 

01

CHALLENGE

  1. 
 How can I automate my work
    and spend more time on
    science?

  2. 
 How can I get easy access to
    the data     from my bioprocess?

  3. 
 How can I use advanced
    analytics, ML     and AI in my lab?

  4. 
 How can I save lab
    workspace    ?

02

SOLUTIONS

Example processes
in which cube sets can be used:
  • Cell cultivation in bioreactor
  • Microalgae cultivation
  • Production of monoclonal antibodies
  • Fermentation
  • Production of antibiotics

03

CUBE BIOREACTOR SETUP

Upgrade you lab
with our modular
equipment!

Cube Edge

Cube Edge

Main unit, provides power
and data connection to
all connected devices.

Edge is required for
connecting other devices
of our biotechnology setup.

  • Touchscreen with basic info about cubes
  • Operate with up to 3 Cubes
  • Wireless connection with end-user devices
  • Remote support via connection
  • Modular Control Platform App with Lab-oriented capabilities

Cube Multisensor

Cube Multisensor

Innovative and advanced device
designed to effortlessly gather
precise data from various
sensors utilizing the Modbus
RS485 communication protocol.

  • Up to 6 digital sensors
  • Compatible with Hamilton and Mettler Toledo probes by default**
  • Zero config, plug & play
  • Works with Cube Edge out of the box
  • One cable for power & data

Cube Multiscale

Cube Multiscale

Exceptional device engineered
to efficiently gather data
from industrial scales through
the RS232 communication protocol.

  • Up to 6 industrial scales
  • Compatible with Mettler Toledo scales by default*
  • Zero config, plug & play
  • Works with Cube Edge out of the box
  • One cable for power & data

Cube Pump

Cube Pump

Stands as an advanced peristaltic
pump device designed to
deliver exceptional performance and
unparalleled versatility.

  • 0.0033 - 365.69mL/min
  • 0.1 - 300rpm
  • Tubes from 0.8x1.6 to 3.1x1.6 mm
  • Zero config, plug & play
  • Works with Cube Edge out of the box
  • One cable for power & data

Cube Led Controller

Cube Led Controller

Used to regulate the lighting
conditions within bioreactors
or cultivation systems that
utilize light for biological processes.

  • Up to 2 independent LED Modules
  • Color temperature 4000K
  • Luminous flux: min. 55 μmol/s max. 900 PPFD Min. 2800 lx max. 40 000 lx
  • Measured at a distance of 1 cm from the light source
  • Zero config, plug & play
  • Works with Cube Edge out of the box
  • One cable for power & data

Cube Led Sparger

Cube Led Sparger

Device used to introduce gases
into liquids. It operates by
dispersing gas in the form
of fine bubbles into
the liquid medium, enhancing
gas-liquid contact and
facilitating processes such as
aeration and fermentation.

  • Up to 3 independent channels
  • From 100SCCM to 100SLPM
  • 9 gases: air, N2, O2, CH4, He, H2, Ar, CO2, N2O
  • Operating pressure up to 145 PSIA
  • Zero config, plug & play
  • Works with Cube Edge out of the box
  • One cable for power & data

04

DIGITAL FUNCTIONS

Why choose our products:

  • Data integration

    All sensors are connected to
    a single software platform
    for data visualization.

  • Remote Monitoring &
    Process
    Control

    Live online view of culture
    parameters with the ability
    to change them.

  • Plug & Play exchangable
    components

    Easily replace faulty
    components without
    stopping the bioprocess or
    servicing the bioreactor.

  • Modular equipment

    Quickly adapt bioreactor
    components to cultivation
    needs as easy as building
    blocks.

  • Data Collection and
    Visualization

    All data is collected
    in one place for easy access,
    analysis, and sharing.

  • Expandable

    Easily add new devices
    to the system without extensive
    reconfiguration.

  • User-friendly interface

    Well-designed application interface
    enhances user experience and
    speeds up the training process.

05

DEVICE FUNCTIONS

Collecting various
types of data from
the bioprocess:
  • pH
  • Temperature
  • DO
  • Cell Density
  • CO2
  • Fluid pumping
  • LED lighting
  • Aeration
  • Flow measurements
  • Temperature control
  • Monitoring environmental parameters (e.g. temperature, humidity)

07

USE CASES

Versatile Bioreactor for Cell
Culture and Fermentation

08

FAQ

What is bioprocessing?

Bioprocessing is defined as the production of value-added substances utilizing living cells, microorganisms, or their components (e.g., enzymes). Penicillium chrysogenum produces penicillin, an illustrative example of bioprocessing.

What is bioreactor fermentation?

The biochemical reaction of anaerobic decomposition of organic compounds by enzymes produced by microorganisms allows microorganisms to obtain the energy they need for their life processes.

What is cell culture?

Cell culture is the process of growing cells outside their natural environment under controlled laboratory conditions. CHO (Chinese hamster ovary) cell cultures are an example of such cultures widely used in biopharmaceutical production.

What is cell culture media?

Microbial and cell culture media contain all the essential ingredients required for the development and growth of cultured organisms. The primary cell culture medium contains the amino acids, glucose, and ions (calcium, magnesium, potassium, sodium, and phosphate) necessary for cell survival and growth. L-glutamine is an essential amino acid for protein and nucleic acid synthesis and energy production in cell culture.

What is a bioreactor?

A bioreactor is a vessel that enables cells or microorganisms to be cultured under controlled conditions to produce the desired product. The control parameters may include gas supply, temperature, pH, and agitation.

Bioreactor vs Photobioreactor - what's the difference?

The photobioreactor design technically differs because it has a light source, which can be integrated light-emitting diodes (LEDs) or separate panels. Bioreactors can support different types of microorganisms and plant or animal cells, while photobioreactors are mainly designed for photosynthesizing organisms.

What are the challenges of bioreactor-driven processes?

  • - Contamination and infection are among the biggest challenges when conducting bioreactor processes. Maintaining internal sterility during all stages of bioproduction is extremely important and affects the final product and bioproduction efficiency.
  • - Human error - errors in media preparation, bioreactor handling, or sampling can result in contamination or inappropriate culture conditions.
  • - Optimization of conditions and scalability - when scaling up to larger bioreactors, culture conditions such as mixing, aeration, and media composition need to be adjusted.
  • - Monitoring and control of bioprocesses. The complexity and sensitivity of biological systems, high sterility requirements, and difficulties with real-time measurements all make it necessary to have advanced technology and expertise to maintain optimal production conditions.

How do I choose the right bioreactor?

When you're picking the right bioreactor, it's essential to think about:
  • - What kind of microorganism you're working with (yeast, bacteria, algae, cell lines)
  • - What the microorganism needs (e.g., phototrophic organisms will require a light source)
  • - Scale (lab scale, pilot scale, industrial scale)
  • - How you want to culture the microorganism (batch, feed-batch, continuous)
  • - The type of bioreactor
  • - A monitoring and control system
  • - Which material do you prefer for constructing the reactor (such as steel, glass, or single-use plastic)
Our team can help you choose the right bioreactor for your needs.

How can we help you?

Before we start, we would like to better understand your needs. Please fill out and send a form.
Our consultant will contact you.

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